"In collaboration with scientists from Harvard University, Prof. Susan Mango’s team at the Biozentrum, University of Basel, has developed a method to trace the chromosomes in individual cells. Using this method, they have now been able to demonstrate that chromosomes reorganize during embryonic development. The study has recently been published in "Molecular Cell".


“Using chromosome tracing, we were able to map the whole 3D chromosome architecture and could show for the first time that chromosomes rearrange during early development, a maturation process that requires the nuclear lamina.”

"The reorganization of the chromosomes accompanies cell maturation and represents a milestone in the development of a complex organism. The correct chromosomal architecture is crucial to prevent developmental disorders."